Diogo Castro - Short Bio

diogo castro

Diogo Castro heads the Molecular Neurobiology laboratory at Instituto Gulbenkian de Ciência. Research in his group is focused on the gene regulatory networks (GRNs) that operate during vertebrate nervous system development, at the transition from proliferating neural stem cells to differentiating neurons and glia. A particular interest has been placed on sequence-specific transcription factors of the bHLH/proneural and Zeb families and how these control maintenance and differentiation of progenitors. In addition, he is also interested in understanding how such important developmental regulators may be used in a malignant cell context, using glioblastoma (the most common and aggressive form of brain cancer in adults) as a model system.